A recent study analyzed data from the UK general medicine registry for the period 1999-2008, focusing on brain stroke patients for the first time in their clinical history (32,151 patients). A clear reduction was observed, from 1.48 per 1000 patients per year in 1999 to 1.04 per 1000 patients per year in 2008 (p <0.001). Stroke mortality decreased from 21% in 1999 to 12% in 2008. While the use of antihypertensive and cholesterol lowering drugs appears timely and appropriate, it is not comforting that anticoagulation was prescribed only to 25% of patients with Atrial Fibrillation and high risk of stroke, while it was sometimes prescribed to patients without a strict indication.